Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-chloro-N-methylacetamide → 2-{6-Chloro-3-[4-(2-trifluoromethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N-methyl-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-chloro-N-methylacetamide | HCID 66773 | — |
| 반응물 | (6-chloro-1H-indol-3-yl)-[4-(2-trifluoromethoxy-phenyl)-piperidin-1-yl]-methanone | HCID 59429664 | — |
| 생성물 | 2-{6-Chloro-3-[4-(2-trifluoromethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N-methyl-acetamide | HCID 16062830 | — |
반응 단계
Analogous to general procedure I, the coupling of (6-chloro-1H-indol-3-yl)-[4-(2-trifluoromethoxy-phenyl)-piperidin-1-yl]-methanone (prepared herein) with (commercially available) 2-chloro-N-methyl-acetamide gave the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07781436B2 |
| 출처 데이터셋 | uspto-grants-2010_08 |
| ORD ID | ord-9ccaf909647948a9bbb54841508bd4e1 |
| 출처 메모 | uspto-grants-2010_08 |