Ethanamine, 2-chloro-N-methyl- → HCID 16062961, 화합물

HRID 505144노트

반응식

HRID 505144 반응식
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]([N:13]3[CH2:18][CH2:17][CH:16]([C:19]4[C:27]5[O:26][CH2:25][CH2:24][C:23]=5[CH:22]=[CH:21][CH:20]=4)[CH2:15][CH2:14]3)=[O:12])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.Cl[CH2:29][CH2:30][NH:31][CH3:32]>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]([N:13]3[CH2:14][CH2:15][CH:16]([C:19]4[C:27]5[O:26][CH2:25][CH2:24][C:23]=5[CH:22]=[CH:21][CH:20]=4)[CH2:17][CH2:18]3)=[O:12])=[CH:7][N:8]2[CH2:29][CH2:30][NH:31][CH3:32])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 20652Ethanamine, 2-chloro-N-methyl-HCID 59429622HCID 59429622, 화합물

생성물 1

HCID 16062961HCID 16062961, 화합물

실험 절차

Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,3-dihydro-benzofuran-7-yl)-piperidin-1-yl]-methanone (preparation described herein), with (commercially available) (2-chloro-ethyl)-methyl-amine gave the title compound.

출처 및 근거

ORD 기록
ord-f6d6ab22fefa469e9ca840f9357d0f32
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07781436B2

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