Bromoacetic Acid → HCID 66743654, 화합물

HRID 505166노트

반응식

HRID 505166 반응식
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]([N:13]3[CH2:18][CH2:17][N:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=4[O:25][CH3:26])[CH2:15][CH2:14]3)=[O:12])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.Br[CH2:28][C:29]([OH:31])=[O:30]>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]([N:13]3[CH2:18][CH2:17][N:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=4[O:25][CH3:26])[CH2:15][CH2:14]3)=[O:12])=[CH:7][N:8]2[CH2:28][C:29]([OH:31])=[O:30])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 6227Bromoacetic AcidHCID 16063356(6-Chloro-1H-indol-3-yl)[4-(2-methoxyphenyl)piperazin-1-yl]methanone

생성물 1

HCID 66743654HCID 66743654, 화합물

실험 절차

Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2-methoxy-phenyl)-piperazin-1-yl]-methanone (preparation described herein), with (commercially available) bromo-acetic acid gave the title compound.

출처 및 근거

ORD 기록
ord-d07894d01ccf4e29bd892ec70895feb5
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07781436B2

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