Potassium Carbonate → 1-Bromo-4-[3-(perfluoro-n-octyl)phenoxy]but-2-ene

HRID 50521

반응식

HRID 50521 반응식
[F:1][C:2]([F:32])([C:25]1[CH:26]=[C:27]([OH:31])[CH:28]=[CH:29][CH:30]=1)[C:3]([F:24])([F:23])[C:4]([F:22])([F:21])[C:5]([F:20])([F:19])[C:6]([F:18])([F:17])[C:7]([F:16])([F:15])[C:8]([F:14])([F:13])[C:9]([F:12])([F:11])[F:10].C(=O)([O-])[O-].[K+].[K+].[Br:39][CH2:40][CH:41]=[CH:42][CH2:43]Br>CN1C(=O)CCC1>[Br:39][CH2:40][CH:41]=[CH:42][CH2:43][O:31][C:27]1[CH:28]=[CH:29][CH:30]=[C:25]([C:2]([F:32])([F:1])[C:3]([F:23])([F:24])[C:4]([F:21])([F:22])[C:5]([F:19])([F:20])[C:6]([F:17])([F:18])[C:7]([F:16])([F:15])[C:8]([F:14])([F:13])[C:9]([F:12])([F:11])[F:10])[CH:26]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 131802-Butene, 1,4-dibromo-HCID 128719693-(Perfluoro-n-octyl)phenol

생성물 1

HCID 865836481-Bromo-4-[3-(perfluoro-n-octyl)phenoxy]but-2-ene

시약·촉매·용매 1

HCID 13387N-methyl-2-pyrrolidone용매

반응 조건

온도
45 °C

실험 절차

A mixture of 3-(perfluoro-n-octyl)phenol (10.24 g), potassium carbonate (4.2 g), NMP (30 mL) and 1,4-dibromo-2-butene (12.8 g) is heated to 45° C. for 2 hr. Extraction in the normal fashion and Kugelrohr distillation of the excess dibromide (0.1 mm Hg, 80° C.) gives 1-bromo-4-[3-(perfluoro-n-octyl)phenoxy]but-2-ene.

후처리

  1. extractionExtraction
  2. distillationin the normal fashion and Kugelrohr distillation of the excess dibromide (0.1 mm Hg, 80° C.)

출처 및 근거

ORD 기록
ord-84a43e43aa6842019dd1ac4de1b6e22c
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06713135B2

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