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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 505759생성일: 2026년 10월 26일

(-)-2-Butanol → (+/-)-(3SR,3aRS)-((R)-sec-butyl) 2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylate

https://huagongshe.com/reaction/505759

반응식

참여 물질

역할이름HCID투입량
반응물(-)-2-ButanolHCID 84682—
반응물(+/-)(3SR,3aRS)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acidHCID 24983760—
생성물(+/-)-(3SR,3aRS)-((R)-sec-butyl) 2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylateHCID 6880024768%

반응 단계

The title compound was prepared from (±)-(3SR,3aRS)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid, Example 15 and (R)-butan-2-ol according to Method E (yellow solid, 155 mg, 0.326 mmol, 68% yield). ES-HRMS m/z calc. for C28H31ClN3O2 (M+H) 476.2099, found 476.2100.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07781428B2
출처 데이터셋uspto-grants-2010_08
ORD IDord-1804d183a7df4d24968994cfede87a89
출처 메모uspto-grants-2010_08