7-Methyl-1H-indol-5-amine → 5-(3,4-dimethoxyphenyl)-4-(7-methyl-1H-indol-5-ylamino)nicotinonitrile
반응식
BrC1C=C(C2C=NC=C(C=2NC2C=C3C(=CC=2)NC=C3)C#N)C=CC=1.Cl[C:27]1[C:32]([C:33]#[N:34])=[CH:31][N:30]=[CH:29][C:28]=1[C:35]1[CH:40]=[CH:39][C:38]([O:41][CH3:42])=[C:37]([O:43][CH3:44])[CH:36]=1.[NH2:45][C:46]1[CH:47]=[C:48]2[C:52](=[C:53]([CH3:55])[CH:54]=1)[NH:51][CH:50]=[CH:49]2>>[CH3:44][O:43][C:37]1[CH:36]=[C:35]([C:28]2[CH:29]=[N:30][CH:31]=[C:32]([C:27]=2[NH:45][C:46]2[CH:47]=[C:48]3[C:52](=[C:53]([CH3:55])[CH:54]=2)[NH:51][CH:50]=[CH:49]3)[C:33]#[N:34])[CH:40]=[CH:39][C:38]=1[O:41][CH3:42]참가 물질
4
실험 절차
Following procedures analogous to those described for preparing compound 113 (Example 2, Method B), the title compound was prepared from 4-chloro-5-(3,4-dimethoxyphenyl)nicotinonitrile and 5-amino-7-methylindole. MS: 385.3 (M+H).