2-Methyl-5-nitro-1H-indole → 5-Amino-2,4-dimethylindole

HRID 506181노트

반응식

HRID 506181 반응식
[CH3:1][Mg+].[Br-].[CH3:4][C:5]1[NH:6][C:7]2[C:12]([CH:13]=1)=[CH:11][C:10]([N+:14]([O-])=O)=[CH:9][CH:8]=2>[Pd]>[NH2:14][C:10]1[C:11]([CH3:1])=[C:12]2[C:7](=[CH:8][CH:9]=1)[NH:6][C:5]([CH3:4])=[CH:13]2

참가 물질

4

반응물 2

HCID 2803132-Methyl-5-nitro-1H-indoleHCID 178418689HCID 178418689, 화합물

생성물 1

HCID 684476445-Amino-2,4-dimethylindole

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

Addition of MeMgBr to 2-methyl-5-nitroindole followed by hydrogenation over Pd/C provided 5-amino-2,4-dimethylindole.

출처 및 근거

ORD 기록
ord-d56d15a7b11a485490d36152fb31697e
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07781591B2

반응 노트

불러오는 중…