Benzaldehyde → 4-(2-(Diethylamino)-Ethoxy)-Benzaldehyde

HRID 506578

반응식

HRID 506578 반응식
[OH-:1].[K+].Cl.Cl[CH2:5][CH2:6][N:7]([CH2:10][CH3:11])[CH2:8][CH3:9].[CH:12](=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(O)C.O>[CH2:8]([N:7]([CH2:10][CH3:11])[CH2:6][CH2:5][O:1][C:16]1[CH:17]=[CH:18][C:13]([CH:12]=[O:19])=[CH:14][CH:15]=1)[CH3:9]

참가 물질

6

반응물 3

HCID 240BenzaldehydeHCID 133631-Chloro-2-(diethylamine)ethane hydrochlorideHCID 14797Potassium Hydroxide

생성물 1

HCID 4116744-(2-(Diethylamino)-Ethoxy)-Benzaldehyde

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

4.82 g potassium hydroxide were dissolved in 70 ml ethanol and treated with 8.46 g (2-Chloro-ethyl)-diethyl-amine hydrochloride. The mixture was stirred until everything was dissolved, then 5.0 g benzaldehyde were added and refluxed for 16 hrs. The mixture was diluted with water and extracted with ethyl acetate, and the organic phases washed several times with caustic soda. After drying and evaporation of the solvent the crude product was used without further purification.

후처리

  1. dissolutionwas dissolved
  2. temperaturerefluxed for 16 hrs
  3. extractionextracted with ethyl acetate
  4. washthe organic phases washed several times with caustic soda
  5. customAfter drying
  6. customevaporation of the solvent the crude product
  7. customwas used without further purification

출처 및 근거

ORD 기록
ord-ccd87d0fe8414c9aaec4f9b0b134d9ca
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07786113B2

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