(6-Methylpyridazin-3-yl)methanamine → HCID 59432545, 화합물

반응식

[CH:1]([C:4]1[S:8][CH:7]=[N:6][C:5]=1[C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([C:18]2[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][N:19]=2)[CH:17]=1)[C:12]([OH:14])=O)([CH3:3])[CH3:2].[CH3:25][C:26]1[N:31]=[N:30][C:29]([CH2:32][NH2:33])=[CH:28][CH:27]=1>>[CH:1]([C:4]1[S:8][CH:7]=[N:6][C:5]=1[C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([C:18]2[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][N:19]=2)[CH:17]=1)[C:12]([NH:33][CH2:32][C:29]1[N:30]=[N:31][C:26]([CH3:25])=[CH:27][CH:28]=1)=[O:14])([CH3:2])[CH3:3]

참가 물질

반응물 2

HCID 55284503(6-Methylpyridazin-3-yl)methanamine

HCID 59432544HCID 59432544, 화합물

생성물 1

HCID 59432545HCID 59432545, 화합물

실험 절차

3-(5-Isopropyl-thiazol-4-yl)-5-(5-methyl-pyridin-2-yl)-benzoic acid was reacted with C-(6-methyl-pyridazin-3-yl)-methylamine using the procedure of Example 2 to give 3-(5-isopropyl-thiazol-4-yl)-N-(6-methyl-pyridazin-3-ylmethyl)-5-(5-methyl-pyridin-2-yl)-benzamide, MS (M+H)=444.

출처 및 근거

ORD 기록: ord-f1983400fc9141e6942a4c8d6ca5291e
출처 데이터셋: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07786110B2

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