Brofoxine → 6-(2-Chlorophenyl)-4,4-dimethyl-1H-benzo[D][1,3]oxazin-2(4H)-one

참여 물질

역할	이름	HCID	투입량
반응물	Brofoxine	HCID 30630	—
반응물	2-Chlorophenylboronic acid	HCID 2734322	—
생성물	6-(2-Chlorophenyl)-4,4-dimethyl-1H-benzo[D][1,3]oxazin-2(4H)-one	HCID 9860721	—

반응 단계

Prepared according to Procedure A from 6-bromo-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one and 2-chlorophenyl boronic acid. White solid: mp 181-182° C.; MS (ESI) m/z 288 ([M+H]+, 70%); Anal. Calc. For C16H14ClNO2: C, 66.79, H, 4.90; N, 4.87. Found: C, 66.78; H, 4.82; N, 4.55.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US06713478B2
출처 데이터셋	uspto-grants-2004_03
ORD ID	ord-360d47bb920e42719b6b7f22147ef8a1
출처 메모	uspto-grants-2004_03