Eltoprazine → 3-{4-[4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-piperazin-1-yl]-butyl}-3-isobutyl-1,3-dihydro-2H-indol-2-one

HRID 506905

반응식

HRID 506905 반응식
Cl[CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([CH2:16][CH:17]([CH3:19])[CH3:18])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]1=[O:15].[O:20]1[C:25]2[CH:26]=[CH:27][CH:28]=[C:29]([N:30]3[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]3)[C:24]=2[O:23][CH2:22][CH2:21]1>>[O:20]1[C:25]2[CH:26]=[CH:27][CH:28]=[C:29]([N:30]3[CH2:35][CH2:34][N:33]([CH2:2][CH2:3][CH2:4][CH2:5][C:6]4([CH2:16][CH:17]([CH3:19])[CH3:18])[C:14]5[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=5)[NH:8][C:7]4=[O:15])[CH2:32][CH2:31]3)[C:24]=2[O:23][CH2:22][CH2:21]1

참가 물질

3

반응물 2

HCID 65853EltoprazineHCID 684633823-(4-Chlorobutyl)-3-isobutyl-1,3-dihydro-2H-indol-2-one

생성물 1

HCID 684651683-{4-[4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-piperazin-1-yl]-butyl}-3-isobutyl-1,3-dihydro-2H-indol-2-one

실험 절차

The title compound is prepared according to process H by applying processing method 1 starting from 3-(4-chlorobutyl)-3-isobutyl-1,3-dihydro-2H-indol-2-one and 4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine.

출처 및 근거

ORD 기록
ord-1e3135eae908467e9018b6ad65d4a5f8
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07786129B2

연결된 노트

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