1-(3-Fluorophenyl)piperazine → 3-Ethyl-3-{4-[4-(3-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydro-chloride

HRID 506932

반응식

HRID 506932 반응식
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([CH2:16][CH3:17])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]1=[O:15].[F:18][C:19]1[CH:20]=[C:21]([N:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:22]=[CH:23][CH:24]=1>>[ClH:1].[CH2:16]([C:6]1([CH2:5][CH2:4][CH2:3][CH2:2][N:28]2[CH2:27][CH2:26][N:25]([C:21]3[CH:22]=[CH:23][CH:24]=[C:19]([F:18])[CH:20]=3)[CH2:30][CH2:29]2)[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]1=[O:15])[CH3:17]

참가 물질

3

반응물 2

HCID 774181-(3-Fluorophenyl)piperazineHCID 670406333-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one

생성물 1

HCID 684679643-Ethyl-3-{4-[4-(3-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one monohydro-chloride

실험 절차

The title compound is prepared according to process H by applying processing method 2 starting from 3-(4-chlorobutyl)-3-ethyl-1,3-di-hydro-2H-indol-2-one and 1-(3-fluorophenyl)-piperazine.

출처 및 근거

ORD 기록
ord-cdce35b5e0dd4accb43eda14c48cd318
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07786129B2

연결된 노트

불러오는 중…