Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromobenzyl cyanide → 2-(4,4-Dimethyl2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)phenylacetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromobenzyl cyanide | HCID 29625 | — |
| 반응물 | (4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid | HCID 10987806 | — |
| 생성물 | 2-(4,4-Dimethyl2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)phenylacetonitrile | HCID 23509611 | — |
반응 단계
Prepared according to procedure B from 2-bromophenylacetonitrile and (1,4-dihydro-4,4-dimethyl-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid. White solid, mp 176-179° C.; 1H-NMR (DMSO-d6), δ 10.31 (s, 1H), 7.53 (m, 1H), 7.48 (m, 2H), 7.22-7.32 (m, 3H), 6.98 (d, 1H; J=8.0 Hz), 3.90 (s, 2H), 1.64 (s, 6H). MS(+)APCI [M+H]+m/z=293. Anal. Calc. For C18H16N2O2: C, 73.95; H, 5.52; N, 9.58. Found: C, 73.51; H, 5.70; N, 9.39.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713478B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-95c4cf808b1f41e183d21e61c6141e56 |
| 출처 메모 | uspto-grants-2004_03 |