Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromobenzene-1-sulfonamide → 3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromobenzene-1-sulfonamide | HCID 2734765 | — |
| 반응물 | (4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid | HCID 10987806 | — |
| 생성물 | 3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)benzenesulfonamide | HCID 12094506 | — |
반응 단계
Prepared according to procedure B from 3-bromobenzenesulfonamide and (1,4-dihydro-4,4-dimethyl-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid. White solid: mp 242-244° C. (dec) 1H-NMR (DMSO-d6) δ 10.28 (s, broad 1H), 8.07(s, 1H), 7.9(d, 1H, J=7.80 Hz), 7.78 (d, 1H, J=7.86 Hz), 7.64 (t, 1H, J=7.79 Hz), 7,59 (m, 2H), 7.42(s, broad 2H), 7.02(d, 1H, J=8.86 Hz), 1.68 (s, 6H); MS m/z 331 (M+H). Anal. Calc. for C16H16N2O4S: C, 57.82; H, 4.85; N, 8.43. Found: C, 57.49; H, 5.08; N, 8.05.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713478B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-e5ec85c9d1e54d6281832b6fb384e4ce |
| 출처 메모 | uspto-grants-2004_03 |