tert-Butyl 2-(2-nitrophenylamino)ethylcarbamate → tert-Butyl 2-[(2-Aminophenyl)amino]ethylcarbamate
반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][CH2:11][CH2:12][NH:13][C:14](=[O:20])[O:15][C:16]([CH3:19])([CH3:18])[CH3:17])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][CH2:11][CH2:12][NH:13][C:14](=[O:20])[O:15][C:16]([CH3:18])([CH3:17])[CH3:19]참가 물질
4
실험 절차
A mixture of tert-butyl 2-(2-nitrophenylamino)ethylcarbamate (400 mg) and palladium (10% on activated carbon, 20 mg) in ethanol (50 mL) was stirred under hydrogen (1 atm) for 5 h. The mixture was filtered through Celite and washed with methanol. The solvent was removed and the product was used in the next step without further purification.
후처리
- filtrationThe mixture was filtered through Celite
- washwashed with methanol
- customThe solvent was removed
- customthe product was used in the next step without further purification
출처 및 근거
- ORD 기록
- ord-96d2a206475748518f07ac99590e1f55
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07786132B2
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