Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(2-Aminoethyl)ethyleneurea → HCID 60204268, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(2-Aminoethyl)ethyleneurea | HCID 80480 | — |
| 반응물 | HCID 15141655 | HCID 15141655 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | HCID 60204268 | HCID 60204268 | 68% |
반응 단계
A mixture of 4-(5-bromothiophen-2-yl)-2-chloropyrimidine (1.0 g, 3.63 mmol), 1-(2-aminoethyl)imidazolidin-2-one (0.47 g, 3.63 mmol) and triethylame (0.44 g, 4.36 mmol) in isopropanol (25 mL) was refluxed for 30 h. After cooling down to rt the precipitate was filtered and washed with methanol (5 mL) and dried to give the title compound as a yellow solid (0.9 g, 68%). MS (M+H)+ 368/370.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07786132B2 |
| 출처 데이터셋 | uspto-grants-2010_08 |
| ORD ID | ord-177cb6d9dcaf40178917a7289810f389 |
| 출처 메모 | uspto-grants-2010_08 |