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1,2-Dichloroethane → HCID 178519697, 화합물

HRID 507925
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인쇄 미리보기

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HRID 507925 반응식
[C:1]1([C:7]2[N:8]=[C:9]([CH:12]=O)[S:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][OH:22])=[CH:17][CH:16]=1.C(O)(=O)C.ClCCCl>CCCCCC>[C:1]1([C:7]2[N:8]=[C:9](/[CH:12]=[N:14]/[C:15]3[CH:20]=[CH:19][C:18]([CH2:21][OH:22])=[CH:17][CH:16]=3)[S:10][CH:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 693314-Aminobenzyl alcoholHCID 35388144-Phenyl-1,3-thiazole-2-carbaldehyde

생성물 1

HCID 178519697HCID 178519697, 화합물수율 88.3%

시약·촉매·용매 1

HCID 8058Hexane용매

실험 절차

A mixture of 4-phenyl-1,3-thiazole-2-carbaldehyde (1.10 g, 5.81 mmol), (4-aminophenyl)methanol (615 mg, 5.0 mmol), acetic acid (0.4 mL) and 1,2-dichloroethane (10 mL) was stirred at room temperature for 30 min. The reaction mixture was diluted with hexane. The precipitated solid was collected by filtration, washed with hexane, and dried to give the title compound (1.30 g, yield 88%) as yellow crystals.

후처리

  1. filtrationThe precipitated solid was collected by filtration
  2. washwashed with hexane
  3. customdried

출처 및 근거

ORD 기록
ord-c030fbe8d23e465e8c1700c584484805
출처 데이터셋
uspto-grants-2010_08
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07786165B2

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