Oxalyl chloride → 4-Chloro-2-fluorobenzoyl isocyanate

HRID 508840

반응식

HRID 508840 반응식
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[C:4]([F:11])[CH:3]=1.C(Cl)(=O)[C:13](Cl)=[O:14]>C(Cl)CCl>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:8]=[C:13]=[O:14])=[O:7])=[C:4]([F:11])[CH:3]=1

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 37218494-Chloro-2-fluorobenzamide

생성물 1

HCID 545417254-Chloro-2-fluorobenzoyl isocyanate

시약·촉매·용매 1

HCID 111,2-Dichloroethane용매

실험 절차

The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 4-chloro-2-fluorobenzamide (0.200 g, 1.26 mmol), EDC (10 mL) and oxalyl chloride (0.14 mL, 1.15 mmol) to afford 0.200 g of the product.

출처 및 근거

ORD 기록
ord-5b16b3dc9e0f47f39dcc6165e7ea013a
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09096545B2

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