Oxalyl chloride → 4-Chloro-2-fluorobenzoyl isocyanate
반응식
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[C:4]([F:11])[CH:3]=1.C(Cl)(=O)[C:13](Cl)=[O:14]>C(Cl)CCl>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([N:8]=[C:13]=[O:14])=[O:7])=[C:4]([F:11])[CH:3]=1참가 물질
4
실험 절차
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 4-chloro-2-fluorobenzamide (0.200 g, 1.26 mmol), EDC (10 mL) and oxalyl chloride (0.14 mL, 1.15 mmol) to afford 0.200 g of the product.
출처 및 근거
- ORD 기록
- ord-5b16b3dc9e0f47f39dcc6165e7ea013a
- 출처 데이터셋
- uspto-grants-2015_08
- 특허 번호
- US09096545B2
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