Ammonia → 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4 methoxybenzamide
반응식
[F:1][C:2]([F:20])([F:19])[C:3]([NH:5][CH2:6][C:7]1[C:8]([O:17][CH3:18])=[CH:9][C:10]([Cl:16])=[C:11]([CH:15]=1)[C:12](O)=[O:13])=[O:4].C(Cl)(=O)C(Cl)=O.[NH3:27]>C1COCC1>[F:1][C:2]([F:20])([F:19])[C:3]([NH:5][CH2:6][C:7]1[C:8]([O:17][CH3:18])=[CH:9][C:10]([Cl:16])=[C:11]([CH:15]=1)[C:12]([NH2:27])=[O:13])=[O:4]참가 물질
5
실험 절차
The title compound was prepared according to the procedure described in step-2 of Intermediate-26 by using 5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid (1.0 g), oxalyl chloride (1.0 mL), THF (50 mL) and ammonia gas to afford 0.800 g of the desired product.
후처리
- customThe title compound was prepared
출처 및 근거
- ORD 기록
- ord-3a8b389a7d584858bb11abcabda97618
- 출처 데이터셋
- uspto-grants-2015_08
- 특허 번호
- US09096545B2
반응 노트
불러오는 중…