Oxalyl chloride → 3-Fluoro-4-(trifluoromethyl)benzoyl isocyanate

HRID 508894

반응식

HRID 508894 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[C:11]([F:14])([F:13])[F:12])[C:5]([NH2:7])=[O:6].C(Cl)(=O)[C:16](Cl)=[O:17]>C(Cl)CCl>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[C:11]([F:12])([F:13])[F:14])[C:5]([N:7]=[C:16]=[O:17])=[O:6]

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 27375433-Fluoro-4-(trifluoromethyl)benzamide

생성물 1

HCID 900198623-Fluoro-4-(trifluoromethyl)benzoyl isocyanate

시약·촉매·용매 1

HCID 111,2-Dichloroethane용매

실험 절차

The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 3-fluoro-4-(trifluoromethyl)benzamide (0.200 g), oxalyl chloride (0.025 mL) and EDC (15 mL) to afford 0.150 g of the desired product.

후처리

  1. customThe title compound was prepared

출처 및 근거

ORD 기록
ord-74361060740d4bcb80adf5f17efd1456
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09096545B2

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