Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluoro-2-nitroaniline → (E)-5-Fluoro-1-(2-pyridyl)-2-styryl-1H-benzimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluoro-2-nitroaniline | HCID 67769 | — |
| 반응물 | (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole | HCID 22736704 | — |
| 생성물 | (E)-5-Fluoro-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 22736771 | — |
반응 단계
The titled compound was prepared from 4-fluoro-2-nitroaniline according to the preparation of (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole (Example 57). MW: 315.35; mp: 134.0-135.0° C.; 1H-NMR (CDCl3) δ: 8.78 (1H, ddd, J=4.8, 1.8, 1.1 Hz), 8.04-7.96 (1H, m), 8.00 (1H, d, J=15.8 Hz), 7.54-7.45 (5H, m), 7.42-7.30 (4H, m), 7.10 (1H, d, J=16.1 Hz), 7.01 (1H, td, J=9.2, 2.6 Hz).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713482B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-46e25139ab334712ae031c4c25160f25 |
| 출처 메모 | uspto-grants-2004_03 |