참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methyl 4-aminobenzoate | HCID 12082 | — |
| 반응물 | Tin tetrachloride | HCID 24287 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Methyl 4-hydrazinylbenzoate | HCID 408928 | 112.7% |
반응 단계
Methyl 4-aminobenzoate (5.0 g, 0.0331 moles) was taken up in conc. HCl (50 mL) and cooled to 0° C. Sodium nitrite (2.5 g, 0.0331 moles) solution in water was added at 0° C. over 30 minutes and stirred at RT for 90 min. Tin chloride (19.40 g, 0.0927 moles) in HCl (100 mL) was added drop wise at 0° C. and stirred at RT for 2 hr. The reaction was filtered and the solid obtained was washed with diethyl ether and dried on a rotary evaporator to give 6.2 g, 92.53% yield of Methyl 4-hydrazinylbenzoate as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09096591B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_08 |
|---|
| ORD ID | ord-d718d8b6af2e4695a0699b705791e9c1 |
|---|
| 출처 메모 | uspto-grants-2015_08 |
|---|
