Methanesulfonyl chloride → 4-Cyclohexylbutan-1-ol mesylate

HRID 50985

반응식

[CH:1]1([CH2:7][CH2:8][CH2:9][CH2:10][OH:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:12][S:13](Cl)(=[O:15])=[O:14]>>[CH3:12][S:13]([O:11][CH2:10][CH2:9][CH2:8][CH2:7][CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)(=[O:15])=[O:14]

참가 물질

반응물 2

HCID 31297Methanesulfonyl chloride

HCID 78182Cyclohexanebutanol

생성물 1

HCID 103767534-Cyclohexylbutan-1-ol mesylate

실험 절차

4-Cyclohexyl-1-butyl methanesulfonate was prepared by following the general procedure of Example 43 for mesylation as a colorless oil (734 mg, 95%) from 4-cyclohexyl-1-butanol (515 mg, 3.20 mmol) and methanesulfonyl chloride (540 mg, 4.80 mmol). 1H NMR (CDCl3, 300 MHz) δ0.83-0.90 (m, 2H), 1.13-1.25 (m, 5H), 1.34-1.44 (m, 2H), 1.60-1.76 (m, 8H), 2.99 (s, 3H), 4.21 (t, 2H, J=6.5 Hz) ppm.

출처 및 근거

ORD 기록: ord-da15b6eef5a04c80a6ac9b9303082beb
출처 데이터셋: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06713471B1

연결된 노트

불러오는 중…