Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methoxy-2-nitropyridine → 2-Amino-3-methoxypyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methoxy-2-nitropyridine | HCID 556063 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-Amino-3-methoxypyridine | HCID 9920384 | 98.6% |
반응 단계
3-Methoxy-2-nitro-pyridine (53, 7.00 g, 45.4 mmol) in 100 mL of methanol, was degassed and palladium (0.7 g, 20%) was added. The reaction was stirred at room temperature for one day under a hydrogen balloon. The reaction was filtered through celite and the filtrate concentrated under vacuum to provide the desired compound (54, 5.555 g). MS (ESI) [M+H+]+=125.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09096593B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-9318cbde3ac744f2823c3446eebe84ba |
| 출처 메모 | uspto-grants-2015_08 |