Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → (2S)-2-(4-Methoxybenzylthiomethyl)-1-methylpyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Sodium cyanoborohydride | HCID 5003444 | — |
| 반응물 | (2S)-2-(4-methoxybenzylthiomethyl)pyrrolidine | HCID 57043207 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | (2S)-2-(4-Methoxybenzylthiomethyl)-1-methylpyrrolidine | HCID 57048351 | 41.7% |
반응 단계
The procedure described in Preparation 5-(4) was repeated, but using 2 g of (2S)-2-(4-methoxybenzylthiomethyl)pyrrolidine, 35% formalin and 848 mg of sodium cyanoborohydride in the presence of 44 ml of acetonitrile, to afford 883 mg of the title compound as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242914 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-1fc826cd6595419badb8308649438ba2 |
| 출처 메모 | uspto-grants-1993_09 |