Trifluoroacetic acid → 7-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

HRID 511321노트

반응식

HRID 511321 반응식
C(OC([NH:8][C:9]1[C:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14][C:13]=2[C:12]([C:20]([OH:22])=[O:21])=[CH:11][CH:10]=1)=O)(C)(C)C.C(O)(C(F)(F)F)=O>>[NH2:8][C:9]1[C:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14][C:13]=2[C:12]([C:20]([OH:22])=[O:21])=[CH:11][CH:10]=1

참가 물질

3

반응물 2

HCID 6422Trifluoroacetic acidHCID 672564057-[(Tert-butoxycarbonyl)amino]-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

생성물 1

HCID 672542797-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

실험 절차

The title compound was prepared by deprotecting Compound 116C with TFA. The crude product was taken on to the next step without purification.

후처리

  1. customThe crude product was taken on to the next step without purification

출처 및 근거

ORD 기록
ord-90ff44e86d8349c4b9abbd8ada76d88d
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09096624B2

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