Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → Bis(4-n-pentylcyclohexylsulfonyl)diazomethane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | p-Toluenesulfonyl azide | HCID 13661 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Bis(4-n-pentylcyclohexylsulfonyl)methane | HCID 22737685 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Bis(4-n-pentylcyclohexylsulfonyl)diazomethane | HCID 22737629 | 46% |
반응 단계
In 22.4 g of dimethylformamide were dissolved 22.5 g (0.050 mol) of the bis(4-n-pentylcyclohexylsulfonyl)methane prepared above and 14.8 g (0.075 mol) of p-toluenesulfonylazide. To this solution were added 90.1 g of ethanol and 22.2 g of water. The solution was cooled on an ice bath, to which 2.0 g (0.050 mol) of sodium hydroxide in 23 g of water was added dropwise at a temperature below 5° C. The solution was ripened at the temperature for 6.5 hours. Filtration of the crystals gave 2.6 g of the desired bis(4-n-pentylcyclohexylsulfonyl)diazomethane. The yield was 46%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713612B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-7eaa13038eb44482a5d299dd3d4e07c0 |
| 출처 메모 | uspto-grants-2004_03 |