2,3-Dichlorobenzoic acid → 2,3-Dichloro-N-(1-methyl-4-phenyl-piperidin-4-ylmethyl)-benzamide

HRID 512216노트

반응식

HRID 512216 반응식
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][N:13]1[CH2:18][CH2:17][C:16]([CH2:25][NH2:26])([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:15][CH2:14]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:26][CH2:25][C:16]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:15][CH2:14][N:13]([CH3:12])[CH2:18][CH2:17]1)=[O:6]

참가 물질

3

반응물 2

HCID 57652,3-Dichlorobenzoic acidHCID 343885(1-Methyl-4-phenylpiperidin-4-yl)methanamine

생성물 1

HCID 867162492,3-Dichloro-N-(1-methyl-4-phenyl-piperidin-4-ylmethyl)-benzamide

실험 절차

From 2,3-dichlorobenzoic acid and C-(1-methyl-4-phenyl-piperidin-4-yl)-methylamine. LCMS (MH+): m/z=376.9, tR (minutes, Method A)=0.69

출처 및 근거

ORD 기록
ord-f45e9f4882bf4284b2402c70dbe44af3
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09102591B2

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