2-Chlorobenzoic Acid → 2-Chloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]benzamide

HRID 512246노트

반응식

HRID 512246 반응식
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH:11]1([CH2:14][CH:15]([C:18]2[CH:19]=[N:20][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:22][CH:23]=2)[CH2:16][NH2:17])[CH2:13][CH2:12]1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:17][CH2:16][CH:15]([C:18]1[CH:19]=[N:20][C:21]([C:24]([F:27])([F:25])[F:26])=[CH:22][CH:23]=1)[CH2:14][CH:11]1[CH2:12][CH2:13]1)=[O:6]

참가 물질

3

반응물 2

HCID 83742-Chlorobenzoic AcidHCID 867162843-Cyclopropyl-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine

생성물 1

HCID 867162852-Chloro-N-[3-cyclopropyl-2-[6-(trifluoromethyl)-3-pyridyl]propyl]benzamide

실험 절차

From 2-chlorobenzoic acid and 3-cyclopropyl-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine. LCMS (MH+): m/z=382.9, tR (minutes, Method C)=1.24

출처 및 근거

ORD 기록
ord-5a637f83ff634640b7be596bff6c0b30
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09102591B2

반응 노트

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