2-Chlorobenzoic Acid → 2-chloro-N-((4-(2-methylpyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methyl)benzamide

HRID 512286노트

반응식

HRID 512286 반응식
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:11][C:12]1[N:17]=[CH:16][C:15]([C:18]2([CH2:24][NH2:25])[CH2:23][CH2:22][O:21][CH2:20][CH2:19]2)=[CH:14][N:13]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:25][CH2:24][C:18]1([C:15]2[CH:16]=[N:17][C:12]([CH3:11])=[N:13][CH:14]=2)[CH2:23][CH2:22][O:21][CH2:20][CH2:19]1)=[O:6]

참가 물질

3

반응물 2

HCID 83742-Chlorobenzoic AcidHCID 86716331(4-(2-methylpyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methanamine

생성물 1

HCID 867163322-chloro-N-((4-(2-methylpyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methyl)benzamide

실험 절차

From 2-chlorobenzoic acid and (4-(2-methylpyrimidin-5-yl)tetrahydro-2H-pyran-4-yl)methanamine. LCMS (MH+): m/z=346.1, tR (minutes, Method F)=1.55

출처 및 근거

ORD 기록
ord-0ecde83efef74b2182912948d98bd822
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09102591B2

반응 노트

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