2,3-Dichlorobenzoic acid → 2,3-Di chloro-N-((2-(2-methylpyrimidin-5-yl)tetrahydrofuran-2-yl)methyl)benzamide

HRID 512379노트

반응식

HRID 512379 반응식
[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][C:13]1[N:18]=[CH:17][C:16]([C:19]2([CH2:24][NH2:25])[CH2:23][CH2:22][CH2:21][O:20]2)=[CH:15][N:14]=1>>[Cl:1][C:2]1[C:10]([Cl:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:25][CH2:24][C:19]1([C:16]2[CH:17]=[N:18][C:13]([CH3:12])=[N:14][CH:15]=2)[CH2:23][CH2:22][CH2:21][O:20]1)=[O:6]

참가 물질

3

반응물 2

HCID 57652,3-Dichlorobenzoic acidHCID 86716238(2-(2-Methylpyrimidin-5-yl)tetrahydrofuran-2-yl)methanamine

생성물 1

HCID 867164352,3-Di chloro-N-((2-(2-methylpyrimidin-5-yl)tetrahydrofuran-2-yl)methyl)benzamide

실험 절차

From 2,3-dichlorobenzoic acid and (2-(2-methylpyrimidin-5-yl)tetrahydrofuran-2-yl)methanamine. LCMS (MH+): m/z=366.0, tR (minutes, Method E)=0.52

출처 및 근거

ORD 기록
ord-ad355589ff89447fa33087bb36bf4bf2
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09102591B2

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