4-(2,3-Dimethoxybenzoyl)pyridine → (2,3-Dimethoxyphenyl)(piperidin-4-yl)methanol

HRID 51243

반응식

HRID 51243 반응식
[CH3:1][O:2][C:3]1[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:4]=1[C:5]([C:7]1[CH:12]=[CH:11][N:10]=[CH:9][CH:8]=1)=[O:6]>N1C=CC=CC=1>[OH:6][CH:5]([CH:7]1[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]1)[C:4]1[CH:13]=[CH:14][CH:15]=[C:16]([O:17][CH3:18])[C:3]=1[O:2][CH3:1]

참가 물질

3

반응물 1

HCID 4285494-(2,3-Dimethoxybenzoyl)pyridine

생성물 1

HCID 10890362(2,3-Dimethoxyphenyl)(piperidin-4-yl)methanol

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

In Scheme F, step g, the pyridine and ketone functionality's of 4-(2,3-dimethoxybenzoyl)pyridine (12) are reduced to give 4-[1-hydroxy-1-(2,3-dimethoxyphenyl)methyl]piperidine (11).

출처 및 근거

ORD 기록
ord-789071f41e0344dbb179ad4e6b230728
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06713627B2

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