Isonicotinic Acid → 4-(2,3-Dimethoxybenzoyl)pyridine

HRID 51246

반응식

[N:1]1[CH:6]=[CH:5][C:4]([C:7]([OH:9])=O)=[CH:3][CH:2]=1.[C:10]1([O:18][CH3:19])[C:11](=[CH:14][CH:15]=[CH:16][CH:17]=1)[O:12][CH3:13]>>[CH3:13][O:12][C:11]1[C:10]([O:18][CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=1[C:7]([C:4]1[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=1)=[O:9]

참가 물질

반응물 2

HCID 5922Isonicotinic Acid

HCID 7043Veratrole

생성물 1

HCID 4285494-(2,3-Dimethoxybenzoyl)pyridine

실험 절차

In Scheme H, step d, 4-pyridinecarboxylic acid (18) is reacted with lithiated veratrole to give 4-(2,3-dimethoxybenzoyl)pyridine (12).

출처 및 근거

ORD 기록: ord-b18ab3eab1bb4fed8f9d7a995fcc80a2
출처 데이터셋: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06713627B2

연결된 노트

불러오는 중…