(2-(Difluoromethyl)phenyl)boronic acid → 1-[1-(4-Cyano-phenyl)-ethyl]-5-(3-difluoromethyl-phenyl)-6-methyl-4-oxo-1,4-dihydro-pyridine-3-carboxylic acid

반응식

[C:1]([C:3]1[CH:30]=[CH:29][C:6]([CH2:7][N:8]2[C:13]([CH3:14])=[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([C:21](F)([F:23])[F:22])[CH:16]=3)[C:11](=[O:25])[C:10]([C:26]([OH:28])=[O:27])=[CH:9]2)=[CH:5][CH:4]=1)#[N:2].F[CH:32](F)C1C=CC=CC=1B(O)O.BrC1C(=O)C(C(O)=O)=CN(CC2C=CC(C#N)=CC=2)C=1C.BrC1C(=O)C(C(O)=O)=CN(C(C2C=CC(C#N)=CC=2)C)C=1C>>[C:1]([C:3]1[CH:30]=[CH:29][C:6]([CH:7]([N:8]2[C:13]([CH3:14])=[C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH:21]([F:23])[F:22])[CH:16]=3)[C:11](=[O:25])[C:10]([C:26]([OH:28])=[O:27])=[CH:9]2)[CH3:32])=[CH:5][CH:4]=1)#[N:2]