Potassium Carbonate → 1-[1-(4-Cyano-phenyl)-ethyl]-2-methyl-4-oxo-2'-trifluoromethyl-1,4-dihydro-[3,4']bipyridinyl-5-carboxylic acid methylamide

반응식

[CH3:1][NH:2][C:3]([C:5]1[C:10](=[O:11])[C:9](Br)=[C:8]([CH3:13])[N:7]([CH:14]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)[CH3:15])[CH:6]=1)=[O:4].[F:24][C:25]([F:36])([F:35])[C:26]1[CH:31]=[C:30](B(O)O)[CH:29]=[CH:28][N:27]=1.C([O-])([O-])=O.[K+].[K+]>C(#N)C.CO.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[Pd]>[CH3:1][NH:2][C:3]([C:5]1[C:10](=[O:11])[C:9]([C:30]2[CH:29]=[CH:28][N:27]=[C:26]([C:25]([F:36])([F:35])[F:24])[CH:31]=2)=[C:8]([CH3:13])[N:7]([CH:14]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)[CH3:15])[CH:6]=1)=[O:4]