5-(4-Methyl-3-nitrobenzamido)-2-(naphthalen-2-ylamino)thiazole-4-carboxamide → 5-(3-Amino-4-methylbenzamido)-2-(naphthalen-2-ylamino)thiazole-4-carboxamide

참여 물질

반응 단계

To a mixture of 5-(4-methyl-3-nitrobenzamido)-2-(naphthalen-2-ylamino)thiazole-4-carboxamide (0.07 g, 0.15 mmol) in MeOH-THF (10 mL, 1:1) was added 10% Pd/C (0.014 g) under N2-atmosphere. The mixture was stirred for 16 hrs under hydrogen atmosphere. The insoluble material was then filtered off, and the filtrate was concentrated under reduced pressure to give 0.032 g (49% yield) of the titled compound.

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