1-Bromo-3,5-dimethoxybenzene → 2-(3,5-Dimethoxyphenyl)furan

반응식

Br[C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[C:4]([O:10][CH3:11])[CH:3]=1.[O:12]1[CH:16]=[CH:15][CH:14]=[C:13]1B(O)O>>[CH3:11][O:10][C:4]1[CH:3]=[C:2]([C:13]2[O:12][CH:16]=[CH:15][CH:14]=2)[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=1

참가 물질

반응물 2

HCID 6391871-Bromo-3,5-dimethoxybenzene

HCID 2734357Furan-2-boronic acid

생성물 1

HCID 584320952-(3,5-Dimethoxyphenyl)furan

실험 절차

1-Bromo-3,5-dimethoxybenzene was coupled with 2-furylboronic acid following the procedure for Example 21. 2-(3,5-Dimethoxyphenyl)furan was isolated as a colorless liquid (0.746 g, 79% yield).

출처 및 근거

ORD 기록: ord-d0a0d95fa09440dd9aded04ccde2eca5
출처 데이터셋: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09102643B2

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