3,6-Dichloropyridazine → HCID 76332840, 화합물

HRID 512841

반응식

HRID 512841 반응식
[OH:1][CH2:2][CH2:3][C:4]1[CH:5]=[N:6][NH:7][CH:8]=1.Cl[C:10]1[N:11]=[N:12][C:13](Cl)=[CH:14][CH:15]=1.[F:17][C:18]1[CH:26]=[C:25]2[C:21]([CH2:22][CH2:23][N:24]2[CH:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:26]=[C:25]2[C:21]([CH2:22][CH2:23][N:24]2[CH:27]2[CH2:32][CH2:31][N:30]([C:10]3[N:11]=[N:12][C:13]([N:6]4[CH:5]=[C:4]([CH2:3][CH2:2][OH:1])[CH:8]=[N:7]4)=[CH:14][CH:15]=3)[CH2:29][CH2:28]2)=[CH:20][CH:19]=1

참가 물질

4

반응물 3

HCID 673313,6-DichloropyridazineHCID 42936042-(1H-Pyrazol-4-yl)ethanolHCID 22038384214614-91-2

생성물 1

HCID 76332840HCID 76332840, 화합물

실험 절차

The title compound was prepared following the procedure as described in Example 14, reacting 4-(2-hydroxyethyl)pyrazole, 3,6-dichloropyridazine, and 6-fluoro-1-(piperidin-4-yl)indoline.

출처 및 근거

ORD 기록
ord-a85e883783a3401bad6f51ae0ff43391
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09102669B2

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