참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Fluoro-3-nitrobenzene | HCID 9823 | — |
| 반응물 | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | Tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate | HCID 22330126 | 33.1% |
반응 단계
To a solution of 3-fluoronitrobenzene (2 mL, 18.8 mmol) in DMSO (20 mL) was added Boc-piperazine (10 g, 56.4 mmol), after stirring at 100° C. for 3 days, the mixture was poured to ice water, the resulting precipitate was collected by filtration to give tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate (1.91 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09102625B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_08 |
|---|
| ORD ID | ord-3970f499b7be4a94a6d0505339b2eead |
|---|
| 출처 메모 | uspto-grants-2015_08 |
|---|
