Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate → tert-Butyl 4-(3-aminophenyl)piperazine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate | HCID 22330126 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | tert-Butyl 4-(3-aminophenyl)piperazine-1-carboxylate | HCID 22330182 | — |
반응 단계
To a solution of tert-butyl 4-(3-nitrophenyl)piperazine-1-carboxylate in EtOH (20 mL) and THF (10 mL) was added Pd/C (500 mg), the mixture was charged with H2 (1 atm) and stirred for 16 h. Pd/C was filtered off, the filtrate was concentrated to give tert-butyl 4-(3-aminophenyl)piperazine-1-carboxylate (1.71 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09102625B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-1ed4b68bf7e8475f86a60a9f5e6fa90a |
| 출처 메모 | uspto-grants-2015_08 |