Hydrochloric Acid → 2-Nitro-4-trifluoromethoxy-benzenesulfonyl chloride

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In a similar fashion using route 3a general procedure 10, SOCl2 (0.36 ml, 4.95 mmol) in cold water (2 ml), CuCl (5 mg, 0.05 mmol), 2-nitro-4-(trifluoromethoxy)aniline (200 mg, 0.90 mmol), conc. HCl (2 ml), NaNO2 (90 mg, 1.3 mmol) in water (2 ml) gave the title compound (290 mg) which was used in the next step without further purification. The structure was confirmed by 1H NMR.

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