Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-8-nitroquinoline → 2-Methyl-8-aminoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-8-nitroquinoline | HCID 13433 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-Methyl-8-aminoquinoline | HCID 140457 | 99.1% |
반응 단계
Palladium on carbon (10%, 50 mg) was added to a solution of 2-methyl-8-nitroquinoline (500 mg, 2.66 mmol) in EtOH (40 ml) and the mixture was stirred under an atmosphere of hydrogen for 2 h. The mixture was diluted with MeOH (40 ml), filtered through celite and the filtrate was concentrated in vacuo to give the title compound (417 mg, 99%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09102688B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-f45c7a9960aa43a4b59b1fb9b3311a85 |
| 출처 메모 | uspto-grants-2015_08 |