Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 3-Methyl-8-quinolinamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Ammonium Sulfite | HCID 25041 | — |
| 반응물 | 3-Methylquinolin-8-ol | HCID 4332281 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Methyl-8-quinolinamine | HCID 15783794 | 91.3% |
반응 단계
3-methylquinolin-8-ol (Intermediate 30) (150 mg, 0.9 mmol) and ammonium sulphite (250 mg, 1.8 mmol) were added to aqueous ammonia (3 ml) and heated for 48 h. After cooling, water was added and the mixture was extracted with DCM. The organic phase was dried (Na2SO4) and concentrated in vacuo to give the title compound (130 mg, 86%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09102688B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-deb45c358e1b499eb3e02cc0c03b2144 |
| 출처 메모 | uspto-grants-2015_08 |