Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl mercaptan → 2-(Benzylthio)-3-nitropyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl mercaptan | HCID 7509 | — |
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-(Benzylthio)-3-nitropyridine | HCID 507300 | 96% |
반응 단계
In a similar fashion using route 38 general procedure 92, 2-chloro-3-nitro-pyridine(2 g, 12.7 mmol), Na2CO3 (1.75 g, 16.6 mmol), benzylmercaptan (1.87 g, 15.1 mmol) and EtOH (20 ml) at 90° C. for 4 h gave the title compound (3 g, 96%) which was used in the next step without further purification. The structure was confirmed by 1H NMR.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09102688B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-29ad9f09c69c4c328a084f911264c85c |
| 출처 메모 | uspto-grants-2015_08 |