Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-8-nitroquinazoline → HCID 11462514, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-8-nitroquinazoline | HCID 11458471 | — |
| 반응물 | p-Toluene sulphonyl hydrazine hydrate | HCID 86669768 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 11462514 | HCID 11462514 | 95% |
반응 단계
p-Toluene sulphonyl hydrazine hydrate (390 mg, 2.1 mmol) was added to a solution of 4-chloro-8-nitro-quinazoline 477 (400 mg, 1.91 mmol) in DCM at (10 ml) and the mixture was stirred at room temperature for 24 h. The mixture was concentrated in vacuo and washed with Et20 to give the title compound (650 mg, 95%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09102688B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-df26422ddfb343fabb844c4eb5bb9369 |
| 출처 메모 | uspto-grants-2015_08 |