Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Stannous Chloride → 5-Aminoquinoxaline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Stannous Chloride | HCID 24479 | — |
| 반응물 | Quinoxaline, 5-nitro- | HCID 97512 | — |
| 촉매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Aminoquinoxaline | HCID 85494 | 98.9% |
반응 단계
In a similar fashion using route 2 general procedure 4, 5-nitroquinoxaline 481 (660 mg, 3.76 mmol), SnCl2 (2.14 g, 11.3 mmol), 6N HCl (6 drops) and MeOH (15 ml) for 3 h at 70° C. gave the title compound (540 mg, 98%) which was used in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09102688B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-ecde29430d4f4c6db7d74a6d2fd582e5 |
| 출처 메모 | uspto-grants-2015_08 |