2,6-Difluorophenylacetic acid → HCID 26597788, 화합물

HRID 514565노트

반응식

HRID 514565 반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][C:10]([OH:12])=O.[K+].[CH3:14][O:15][C:16](=[O:21])[CH2:17]C([O-])=O>>[F:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[C:3]=1[CH2:9][C:10](=[O:12])[CH2:17][C:16]([O:15][CH3:14])=[O:21]

참가 물질

3

반응물 2

HCID 1235852,6-Difluorophenylacetic acidHCID 2724687Potassium methyl malonate

생성물 1

HCID 26597788HCID 26597788, 화합물

실험 절차

The title compound was prepared from 2-(2,6-difluorophenyl)acetic acid and 3-methoxy-3-oxopropanoic acid potassium salt according to the procedure for the preparation of Example 170, part A. 1H NMR (300 MHz, CDCl3): δ 3.56 (2H, s), 3.75 (3H, s), 3.92 (2H, s), 6.89-6.93 (2H, m), 7.22-7.27 (1H, m).

출처 및 근거

ORD 기록
ord-b456552adedc472da14de72c70b460e1
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09107916B2

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