Ethyl 4-(3-chlorophenyl)-3-oxobutanoate → HCID 178510216, 화합물

반응식

[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[Cl:11][C:12]1[CH:13]=[C:14]([CH2:18][C:19](=O)[CH2:20][C:21](OCC)=[O:22])[CH:15]=[CH:16][CH:17]=1>>[Cl:11][C:12]1[CH:13]=[C:14]([CH2:18][C:19]2[CH:20]=[C:21]([OH:22])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)[CH:15]=[CH:16][CH:17]=1

참가 물질

반응물 2

HCID 10538052Ethyl 4-(3-chlorophenyl)-3-oxobutanoate

HCID 201187142-Hydrazinylpyridine-4-carbonitrile

생성물 1

HCID 178510216HCID 178510216, 화합물수율 32%

실험 절차

The title compound was prepared in 32% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and ethyl 4-(3-chlorophenyl)-3-oxobutanoate according to the procedure for the preparation of Example 158, part A.

출처 및 근거

ORD 기록: ord-aea66070ef6b4f86bce7d995de328d28
출처 데이터셋: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09107916B2

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