Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine → 5-(4-Phenoxyphenyl)-7-(Tetrahydro-2h-Pyran-4-Yl)-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | HCID 12042234 | — |
| 반응물 | Tetrahydro-2H-pyran-4-yl 4-methylbenzenesulfonate | HCID 13961807 | — |
| 생성물 | 5-(4-Phenoxyphenyl)-7-(Tetrahydro-2h-Pyran-4-Yl)-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine | HCID 22736361 | — |
반응 단계
In a similar manner to Example 1, 4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine was reacted with 4-tosyloxytetrahydropyran to give after flash column chromatography 5-(4-phenoxyphenyl)-7-(4-tetrahydropyranyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, m.p. 193-193.5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06713474B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-5f71a6ff13154370a64cbd284e766552 |
| 출처 메모 | uspto-grants-2004_03 |