2-Methoxyethylamine → HCID 22736271, 화합물
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[NH2:1][C:2]1[C:3]2[C:10]([C:11]3[CH:25]=[CH:24][C:14]([O:15][C:16]4[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=4[CH:18]=O)=[CH:13][CH:12]=3)=[CH:9][N:8]([CH:26]3[CH2:30][CH2:29][O:28][CH2:27]3)[C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:31][O:32][CH2:33][CH2:34][NH2:35]>>[CH3:31][O:32][CH2:33][CH2:34][NH:35][CH2:18][C:17]1[CH:20]=[CH:21][CH:22]=[CH:23][C:16]=1[O:15][C:14]1[CH:13]=[CH:12][C:11]([C:10]2[C:3]3[C:2]([NH2:1])=[N:7][CH:6]=[N:5][C:4]=3[N:8]([CH:26]3[CH2:30][CH2:29][O:28][CH2:27]3)[CH:9]=2)=[CH:25][CH:24]=1참가 물질
3
실험 절차
In a similar manner to Example 10, 2-[4-(4-amino-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d)pyrimidin-5-yl)phenoxy]benzaldehyde (0.15 g) and 2-methoxyethylamine (56 mg) were reacted together to give 5-{4-[2-(2-methoxyethyl)aminomethylphenoxy]phenyl}-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d]-pyrimidin-4-ylamine m.p. 66-68° C. (glassy foam).
출처 및 근거
- ORD 기록
- ord-5543595041b44c40bf670901f8b54d0b
- 출처 데이터셋
- uspto-grants-2004_03